DISEASES

Disease-gene associations mined from literature

Literature associating RGMB and multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly

RGMB [ENSP00000308219]

DRG11-responsive axonal guidance and outgrowth of neurite; Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.

Synonyms:  RGMB,  J3KNF6,  Q6NW40,  J3KNF6p,  hJ3KNF6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM