Disease-gene associations mined from literature

Literature associating RNASEH2C and prolidase deficiency

RNASEH2C [ENSP00000308193]

Aicardi-Goutieres syndrome 3 protein; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Synonyms:  RNASEH2C,  A0A024R5B3,  AYP1,  E9PKP0,  E9PN81 ...

Linkouts:  STRING  Pharos  UniProt  OMIM