DISEASES

Disease-gene associations mined from literature

Literature associating PCSK1 and obesity

PCSK1 [ENSP00000308024]

Proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP; Belongs to the peptidase S8 family. Furin subfamily.

Synonyms:  PCSK1,  PCSK1p,  hPCSK1,  D6RJA3,  P29120 ...

Linkouts:  STRING  Pharos  UniProt  OMIM