DISEASES

Disease-gene associations mined from literature

Literature associating EEF2 and diphtheria

EEF2 [ENSP00000307940]

Eukaryotic translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

Synonyms:  EEF2,  EEF2p,  hEEF2,  B4DMC6,  P13639 ...

Linkouts:  STRING  Pharos  UniProt  OMIM