Literature associating DRAP1 and Renpenning syndrome
DR1-associated protein 1 (negative cofactor 2 alpha); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
Synonyms: DRAP1, DRAP1p, hDRAP1, C9JCC6, E9PMW2 ...