DISEASES

Disease-gene associations mined from literature

Literature associating IRF2BP1 and cecal disease

IRF2BP1 [ENSP00000307265]

Probable RING-type E3 ubiquitin transferase IRF2BP1; Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.

Synonyms:  IRF2BP1,  IRF2BP1p,  hIRF2BP1,  Q8IU81,  Q8IU81p ...

Linkouts:  STRING  Pharos  UniProt  OMIM