Literature associating BPTF and lacrimal gland adenocarcinoma
Bromodomain and PHD finger-containing transcription factor; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors; Belongs to the PBTF family.
Synonyms: BPTF, E7ETD6, F5GXF5, Q12830, Q86TN2 ...