Disease-gene associations mined from literature

Literature associating KIF5B and lung combined large cell neuroendocrine carcinoma

KIF5B [ENSP00000307078]

Conventional kinesin heavy chain; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes; Kinesins

Synonyms:  KIF5B,  KIF5Bp,  hKIF5B,  A8K048,  HEL-S-61 ...

Linkouts:  STRING  Pharos  UniProt  OMIM