DISEASES

Disease-gene associations mined from literature

Literature associating KLF11 and neonatal diabetes mellitus

KLF11 [ENSP00000307023]

Transforming growth factor-beta-inducible early growth response protein 2; Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity); Belongs to the Sp1 C2H2-type zinc-finger protein family.

Synonyms:  KLF11,  KLF11p,  hKLF11,  B5MCC4,  C9JM94 ...

Linkouts:  STRING  Pharos  UniProt  OMIM