DISEASES

Disease-gene associations mined from literature

Literature associating YEATS2 and familial adult myoclonic epilepsy 7

YEATS2 [ENSP00000306983]

YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.

Synonyms:  YEATS2,  YEATS2p,  hYEATS2,  Q9ULM3,  KIAA1197 ...

Linkouts:  STRING  Pharos  UniProt  OMIM