DISEASES

Disease-gene associations mined from literature

Literature associating TMEM135 and familial melanoma

TMEM135 [ENSP00000306344]

Peroxisomal membrane protein 52; Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization; Belongs to the TMEM135 family.

Synonyms:  TMEM135,  TMEM135p,  hTMEM135,  B4DKZ1,  E9PIS2 ...

Linkouts:  STRING  Pharos  UniProt