DISEASES

Disease-gene associations mined from literature

Literature associating ATP5I and complex partial epilepsy

ATP5I [ENSP00000306003]

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

Synonyms:  ATP5I,  ATP5Ip,  hATP5I,  ATP5ME,  P56385 ...

Linkouts:  STRING  Pharos  UniProt  OMIM