DISEASES

Disease-gene associations mined from literature

Literature associating FAM134B and autonomic neuropathy

FAM134B [ENSP00000304642]

Family with sequence similarity 134, member B; Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Required for long-term survival of nociceptive and autonomic ganglion neurons.

Synonyms:  FAM134B,  FAM134Bp,  hFAM134B,  Q9H6L5,  RETREG1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM