DISEASES

Disease-gene associations mined from literature

Literature associating PITX2 and appendicitis

PITX2 [ENSP00000304169]

RIEG bicoid-related homeobox transcription factor; Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity); Belongs to the paired homeobox family. Bicoid subfamily.

Synonyms:  PITX2,  PITX2p,  hPITX2,  A8MUL9,  D6RBG8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM