Literature associating PITX2 and umbilical hernia
RIEG bicoid-related homeobox transcription factor; Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity); Belongs to the paired homeobox family. Bicoid subfamily.
Synonyms: PITX2, PITX2p, hPITX2, A8MUL9, D6RBG8 ...