DISEASES

Disease-gene associations mined from literature

Literature associating UGT1A6 and Crigler-Najjar syndrome

UGT1A6 [ENSP00000303174]

UDP glucuronosyltransferase 1 family, polypeptide A6; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity); Belongs to the UDP-glycosyltransferase family.

Synonyms:  UGT1A6,  UGT1A6p,  hUGT1A6,  B5MCT4,  C9JMY5 ...

Linkouts:  STRING  Pharos  UniProt