Disease-gene associations mined from literature

Literature associating RNASE3 and onchocerciasis

RNASE3 [ENSP00000302324]

Eosinophil cationic protein; Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Synonyms:  RNASE3,  RNASE3p,  hRNASE3,  P12724,  P12724p ...

Linkouts:  STRING  Pharos  UniProt  OMIM