DISEASES

Disease-gene associations mined from literature

Literature associating CYP2A6 and alcoholic liver cirrhosis

CYP2A6 [ENSP00000301141]

Cytochrome P450, family 2, subfamily A, polypeptide 6; Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity; Cytochrome P450 family 2

Synonyms:  CYP2A6,  CYP2A6p,  hCYP2A6,  M0R2Z4,  P11509 ...

Linkouts:  STRING  Pharos  UniProt