Literature associating CYP2A6 and nicotine dependence
Cytochrome P450, family 2, subfamily A, polypeptide 6; Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity; Cytochrome P450 family 2
Synonyms: CYP2A6, CYP2A6p, hCYP2A6, M0R2Z4, P11509 ...