Disease-gene associations mined from literature

Literature associating WNT10B and split hand-foot malformation 6

WNT10B [ENSP00000301061]

Wingless-type MMTV integration site family, member 10B; Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin; Belongs to the Wnt family.

Synonyms:  WNT10B,  WNT10Bp,  hWNT10B,  B5MCC8,  C9J3H3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM