DISEASES

Disease-gene associations mined from literature

Literature associating ANPEP and bone marrow cancer

ANPEP [ENSP00000300060]

Myeloid plasma membrane glycoprotein CD13; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases

Synonyms:  ANPEP,  A0A024RC61,  B4DP96,  B4DV63,  CD13 ...

Linkouts:  STRING  Pharos  UniProt  OMIM