DISEASES

Disease-gene associations mined from literature

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Literature associating MESP1 and dysostosis

MESP1 [ENSP00000300057]

Mesoderm posterior basic helix-loop-helix transcription factor 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity); Basic helix-loop-helix proteins

Synonyms:  MESP1,  MESP1p,  hMESP1,  Q9BRJ9,  Q9NSF0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.