Literature associating PLIN1 and familial partial lipodystrophy type 3
Lipid droplet-associated protein; Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels; Belongs to the perilipin family.
Synonyms: PLIN1, PLIN1p, hPLIN1, H0YM16, O60240 ...