DISEASES

Disease-gene associations mined from literature

Literature associating TK2 and spinocerebellar ataxia type 31

TK2 [ENSP00000299697]

Thymidine kinase 2, mitochondrial; Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 and DGUOK. Widely used as target of antiviral and chemotherapeutic agents; Belongs to the DCK/DGK family.

Synonyms:  TK2,  TK2p,  hTK2,  A4IF54,  E5KNQ5 ...

Linkouts:  STRING  Pharos  UniProt