Disease-gene associations mined from literature

Literature associating TPP1 and spinocerebellar ataxia type 7

TPP1 [ENSP00000299427]

Lysosomal pepstatin-insensitive protease; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity).

Synonyms:  TPP1,  TPP1p,  hTPP1,  D3DQU2,  E7EV34 ...

Linkouts:  STRING  Pharos  UniProt  OMIM