Disease-gene associations mined from literature

Literature associating PRDX3 and Fuchs' endothelial dystrophy

PRDX3 [ENSP00000298510]

Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol; Peroxiredoxins

Synonyms:  PRDX3,  PRDX3p,  hPRDX3,  MER5,  P30048 ...

Linkouts:  STRING  Pharos  UniProt  OMIM