Literature associating SPTSSA and hereditary sensory and autonomic neuropathy type 1A
Small subunit of serine palmitoyltransferase A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2- SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16- CoA as substrates, with a slight preference for C14-CoA.
Synonyms: SPTSSA, Q969W0, C14orf147, Q969W0p, hQ969W0 ...