DISEASES

Disease-gene associations mined from literature

Literature associating FIGF and anal canal squamous cell carcinoma

FIGF [ENSP00000297904]

C-fos induced growth factor (vascular endothelial growth factor D); Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Synonyms:  FIGF,  O43915,  VEGFD,  O43915p,  hO43915 ...

Linkouts:  STRING  Pharos  UniProt  OMIM