DISEASES

Disease-gene associations mined from literature

Literature associating UBAP1 and nasopharynx carcinoma

UBAP1 [ENSP00000297661]

Nasopharyngeal carcinoma-associated gene 20 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.

Synonyms:  UBAP1,  UBAP1p,  hUBAP1,  Q9NZ09,  NAG20 ...

Linkouts:  STRING  Pharos  UniProt