Literature associating ASIC3 and myofascial pain syndrome
ASIC3 [ENSP00000297512]
Acid-sensing ion channel 3; Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
Synonyms: ASIC3, ASIC3p, hASIC3, A0A090N7X8, A0A090N8Q1 ...