DISEASES

Disease-gene associations mined from literature

Literature associating NOS3 and renovascular hypertension

NOS3 [ENSP00000297494]

Nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Synonyms:  NOS3,  NOS3p,  hNOS3,  E7ESA7,  O14937 ...

Linkouts:  STRING  Pharos  UniProt  OMIM