Literature associating DEFB1 and cystic fibrosis
Defensin, beta 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family.
Synonyms: DEFB1, DEFB1p, hDEFB1, P60022, BD1 ...