DISEASES

Disease-gene associations mined from literature

Literature associating MED30 and vestibulocochlear nerve disease

MED30 [ENSP00000297347]

Thyroid hormone receptor-associated protein complex 25 kDa component; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Synonyms:  MED30,  MED30p,  hMED30,  Q96HR3,  Q96HR3p ...

Linkouts:  STRING  Pharos  UniProt  OMIM