Literature associating SHH and pilocytic astrocytoma of cerebellum
Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity); Hedgehog signaling molecule family
Synonyms: SHH, C9JC48, D9ZGF9, F8WB84, F8WEH4 ...