DISEASES

Disease-gene associations mined from literature

Literature associating NKD2 and optic atrophy 8

NKD2 [ENSP00000296849]

Naked cuticle homolog 2 (Drosophila); Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells; EF-hand domain containing

Synonyms:  NKD2,  NKD2p,  hNKD2,  Q969F2,  Q969F2p ...

Linkouts:  STRING  Pharos  UniProt  OMIM