DISEASES

Disease-gene associations mined from literature

Literature associating GFM2 and mitochondrial metabolism disease

GFM2 [ENSP00000296805]

Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

Synonyms:  GFM2,  GFM2p,  hGFM2,  A0A024RAJ7,  A0A024RAK1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM