Literature associating PRDM9 and Potocki-Lupski syndrome
Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity); Lysine methyltransferases
Synonyms: PRDM9, PRDM9p, hPRDM9, D2E453, D2KI85 ...