Literature associating RHO and Leber congenital amaurosis
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Synonyms: RHO, P08100, OPN2, P08100p, hP08100 ...