Literature associating LIPH and multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly
Membrane-associated phosphatidic acid-selective phospholipase A1-alpha; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family.
Synonyms: LIPH, A2IBA6, A2IBA8, F8WE09, Q8WWY8 ...