DISEASES

Disease-gene associations mined from literature

Literature associating LZTFL1 and Bardet-Biedl syndrome 17

LZTFL1 [ENSP00000296135]

Leucine zipper transcription factor-like protein 1; Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function; Belongs to the LZTFL1 family.

Synonyms:  LZTFL1,  LZTFL1p,  hLZTFL1,  C9J0R9,  F2Z2E6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM