DISEASES

Disease-gene associations mined from literature

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Literature associating UCN and intestinal disease

UCN [ENSP00000296099]

Urocortin; Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) . Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta . Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity).

Synonyms:  UCN,  P55089,  P55089p,  hP55089,  2RMF ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.