Literature associating PF4 and essential thrombocythemia
C-X-C motif chemokine 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form; Belongs to the intercrine alpha (chemokine CxC) family.
Synonyms: PF4, PF4p, hPF4, P02776, CXCL4 ...