Disease-gene associations mined from literature

Literature associating HPGDS and inflammatory bowel disease 16

HPGDS [ENSP00000295256]

Glutathione-requiring prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide; Belongs to the GST superfamily. Sigma family.

Synonyms:  HPGDS,  O60760,  PGDS,  Q4W5C6,  GSTS ...

Linkouts:  STRING  Pharos  UniProt  OMIM