Literature associating VCAM1 and cerebrovascular disease
Vascular cell adhesion molecule 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation; C2-set domain containing
Synonyms: VCAM1, VCAM1p, hVCAM1, DKFZP779G2333, E9PDD2 ...