DISEASES

Disease-gene associations mined from literature

Literature associating KCNT2 and hypertrophic cardiomyopathy 1

KCNT2 [ENSP00000294725]

Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1; Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1; Belongs to the potassium channel family. Calcium- activated (TC 1.A.1.3) subfamily. KCa4.2/KCNT2 sub-subfamily.

Synonyms:  KCNT2,  KCNT2p,  hKCNT2,  A9LNM6,  Q3SY61 ...

Linkouts:  STRING  Pharos  UniProt  OMIM