DISEASES

Disease-gene associations mined from literature

Literature associating C11orf84 and chondroid lipoma

C11orf84 [ENSP00000294244]

Chromosome 11 open reading frame 84; Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4.

Synonyms:  C11orf84,  C11ORF84,  H0YGY5,  Q9BUA3,  SPINDOC ...

Linkouts:  STRING  Pharos  UniProt