Disease-gene associations mined from literature

Literature associating AQP5 and aplasia of lacrimal and salivary glands

AQP5 [ENSP00000293599]

Aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells; Belongs to the MIP/aquaporin (TC 1.A.8) family.

Synonyms:  AQP5,  AQP5p,  hAQP5,  P55064,  P55064p ...

Linkouts:  STRING  Pharos  UniProt  OMIM