Literature associating WNT1 and cerebellar hypoplasia
WNT1 [ENSP00000293549]
Proto-oncogene Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation . In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity). Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity). Has a role in osteoblast function, bone development and bone homeostasis . ECO:0000269|PubMed:23656646, ECO:0000269|PubMed:26902720,
Synonyms: WNT1, WNT1p, hWNT1, A0A087WXR9, P04628 ...