DISEASES

Disease-gene associations mined from literature

Literature associating HCRT and Kleine-Levin syndrome

HCRT [ENSP00000293330]

Hypocretin (orexin) neuropeptide precursor; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity; Endogenous ligands

Synonyms:  HCRT,  O43612,  O43612p,  hO43612,  OX ...

Linkouts:  STRING  Pharos  UniProt  OMIM