DISEASES

Disease-gene associations mined from literature

Literature associating CCR5 and bubonic plague

CCR5 [ENSP00000292303]

Chemokine (C-C motif) receptor 5 (gene/pseudogene); Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Synonyms:  CCR5,  CCR5p,  hCCR5,  A1A490,  B8LFN8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM